The first report of Henry's interest in Jane was in February 1536, about three months before Anne's execution. Jane became a maid-of-honour in 1532 to Queen Catherine, but may have served her as early as 1527, and went on to serve Queen Anne with her sister Elizabeth. After her death, it was noted that Henry was an 'enthusiastic embroiderer.' Her needlework was reportedly beautiful and elaborate some of it survived as late as 1652, when it is recorded to have been given to the Seymour family. She could read and write a little, but was much better at needlework and household management, which were considered much more necessary for women. Jane was not as highly educated as Henry's first and second wives, Catherine of Aragon and Anne Boleyn.

She also shared a great-grandmother, Elizabeth Cheney, with his second and fifth wives, Anne Boleyn and Catherine Howard. Because of this, she and King Henry VIII were fifth cousins. Through her maternal grandfather, she was a descendant of King Edward III's son Lionel of Antwerp, 1st Duke of Clarence. Her birth date is not recorded various accounts use anywhere from 1504 to 1509, but it is generally estimated around 1508. Jane, the daughter of Sir John Seymour and Margery Wentworth, was most likely born at Wulfhall, Wiltshire, although West Bower Manor in Somerset has also been suggested.

She was the only wife of Henry to receive a queen's funeral or to be buried beside him in St George's Chapel, Windsor Castle. She died of postnatal complications less than two weeks after the birth of her only child, the future King Edward VI. She became queen following the execution of Henry's second wife, Anne Boleyn. 1508 – 24 October 1537) was Queen of England as the third wife of King Henry VIII of England from their marriage on until her death the next year.

I, Jane by Diane Haeger